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VIAGRA [Sildenafil citrate] An Overview
VIAGRA [Sildenafil citrate] is the only approved and effective oral agent for the treatment of erectile dysfunction. Before that a few lines on erectile dysfunction. Erectile dysfunction [Impotence] is a condition in which erection the penis cannot be achieved during sexual intercourse/masturbation. There are many causes for erectile dysfunction. The most common cause of being increasing age. Other conditions can be: - Diabetes Mellitus - Hypertension - Heart Disease - Atherosclerosis - Lower spinal cord injury - Cancer prostate - Psychogenic - Stress Erection is achieved when there is increased blood flow to penis and hence the main organic cause is disturbance of blood flow to and from the penis. Coming back to VIAGRA [Sildenafil citrate], Viagra is a selective and potent inhibitor of cyclic guanosine monophosphate [cGMP] specific phosphodiesterase type 5 inhibitor [PDE5] which is the predominant phosphodiesterase isoform found in the penis. It is administered in doses of 25, 50 and 100 mg, and enhances erection after sexual stimulation. The onset of action is around 60-90 mins. Sildenafil (compound UK-92,480) was synthesized by a group of chemists working at Pfizer's Sandwich, Kent research facility in England. It was initially studied for use in hypertension and angina pectoris. The first clinical trials were conducted in Morriston Hospital in Swansea. Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections. VIAGRA [Sildenafil citrate] was approved for use in erectile dysfunction by the Food and Drug Administration on March 27, 1998, becoming the first pill approved to treat erectile dysfunction Reduced initial doses should be considered for patients, who are elderly, have renal insufficiency, or are taking medications that inhibit the CYP3A4 metabolic pathway in the liver [e.g., erythromycin, cimetidine, ketoconazole] as they may increase the serum concentration of sildenafil. The drug does not affect ejaculation, orgasm or sexual drive. When sexual stimulation causes local release of NO, inhibition of PDE5 by VIAGRA [Sildenafil citrate] causes increased levels of cGMP in the corpus cavernosum of the penis resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Side Effects: ?? Headaches ?? Facial flushing ?? ringing in ears, or sudden hearing loss ?? Dyspepsia ?? Nasal congestion. ?? Abnormal vision [blue halo effect] ?? Diarrhea ?? Dizziness ?? Rashes Viagra can decrease blood flow to the optic nerve of the eye, causing sudden vision loss:- Special precautions: In patients with ?? Bleeding disorders such as hemophilia ?? Liver disorder ?? Kidney disorder ?? Active peptic ulcerations and ?? Anatomical deformation of the penis, such as peyronie's disease. ?? Retinitis pigmentosa Contraindications: VIAGRA [Sildenafil citrate], is contraindicated in men receiving nitrate therapy for cardiovascular disease, including agents delivered by oral, sublingual, trans-nasal or topical routes. These agents can potentates its hypotensive effect and may result in profound shock. Viagra should be avoided in patients with congestive heart failure and cardiomyopathy because of the risk of vascular collapse.
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Learn More about
Natural Male Enhancements
Sildenafil is introduce in 1998, its better known by its trade name Viagra. It has been one of the most popular prescription medications on the market. It was the first "as needed" pill treatment for erectile dysfunction. The U.S. Food and Drug Administration approved Viagra for erectile dysfunction, but not to prolong erections. Viagra will not help delay ejaculation.
What is Viagra? ... 
VIAGRA [Sildenafil citrate] is the only approved and effective oral agent for the treatment of erectile dysfunction. Before that a few lines on erectile dysfunction. Erectile dysfunction [Impotence] is a condition in which erection the penis cannot be achieved during sexual intercourse/masturbation. There are many causes for erectile dysfunction. The most common cause of being increasing age....
There are many underlying physical and psychological causes of erectile dysfunction. Reduced blood flows to the penis and nerve damage are two of the most common physical causes. Underlying conditions associated with erectile dysfunction include vascular disease, diabetes, drugs, hormone disorders, neurological disorders, pelvic trauma, surgery, radiation therapy, a venous leak or psychological...
Erectile dysfunction is a condition in which a man is unable to maintain enough firmness in his penis to perform sexual intercourse. The condition is also referred to as impotence, however that is inaccurate, for "impotence" refers to any condition which inhibits sexual performance, which can include problems with organs, ejaculation, or even sexual interest. The term erectile dysfunction, refers...
Viagra (Sildenafil) - Erectile dysfunction medication
About Viagra
Viagra is an oral prescription medication approved to treat erectile dysfunction in men. Manufactured by Pfizer, Viagra has helped several men across the globe with their erection and sexual problems.
Viagra can help men with erectile dysfunction to attain and maintain their erection when sexual stimulation complements...
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